Endocrine Abstracts

Objective: The objective of our study is to evaluate muscle strength and risk of falls in type 2 diabetes mellitus (DM2) patientsMethods: Observational cross-sectional study. Hand grip strength (HGS) (kg/cm2) was measured with a Jamar. manual hydraulic dynamometer (5030j1; Jackson, MI). To classify normality, data from the Spanish population were used, establishing the cut-off point at p10. To assess the level of mobility and the risk of ...

Introduction: Bariatric surgery (BS) is an effective method to weight loss, however, some patients experience persistence of physical inactivity or even weight gain over the years. Furthermore, It is not clear if some surgical techniques, mainly those with disabsortive components, could be involved in the low physical performance through interfering with nutritional status This study aimed to evaluate physical function (PF), quality of life (QOL) and energy expenditure (EE) du...

Non alcoholic steatohepatitis (EHNA) is diagnosed by hepatic biopsy. Its etiology is uncertain but obesity is present in 69–100% of all cases and type 2 diabetes mellitus (DM) in about 34–75%.Objectives: To study the prevalence of EHNA in morbidly obese patients and determine if there is a difference between the prevalence in patients with and without carbohydrate metabolism disorders.Patients and methods: Prospective stu...

Metabolic syndrome (MS) is a group of signs that increase the risk of developing cardiovascular diseases and type 2 diabetes mellitus (DM2). MS includes at least 3 of these signs: central obesity, dyslipidemia, hypertension, fasting glucose disorders, and insulin resistance. The consumption of sugar drinks, a high-calorie diet, a sedentary lifestyle, and environmental pollutants such as arsenic increase the risk of developing MS. Arsenic affects beta-cell function and insulin ...

The use of Flash Glucose Monitoring system (FGM) for the management of type 1 diabetes mellitus (T1D) is rapidly increasing. FGM enables people with diabetes to regularly track their glucose levels without needing to perform capillary finger-stick measurements (SMBG). Clinical studies have shown improvement of glycemic control and hypoglycemia reduction, as well as better comfort and quality of life in people with type 1 diabetes (T1D) using this technology. Objectives: to ass...

Background: The complex involvement of multiple metabolic defects in the pathogenesis of type 2 diabetes mellitus (T2DM) makes difficult the treatment in monotherapy, therefore, the use of different antidiabetic drugs with different and complementary mechanisms of action could result in better glycemic control with favorable metabolic changes.Objective: To determine the effectiveness and safety of the addition of a sodium-glucose co-transporter type 2 in...

Background: Cross-sex hormone therapy (CHT) is known to lead to alterations in cardiovascular risk factor(CVRF).Objective: To assess changes in lipid profile and other CVRF in transsexual subjects receiving CHT.Materials and methods: Retrospective longitudinal study. We evaluated individuals with gender identity disorder following CHT, assisted in the Gender Identity Unit from 2015 to 2017. Primary endpoint was lipid profile change...

Introduction: Obesity is a known risk factor for hypovitaminosis D and although several studies point out that higher adherence to the Mediterranean Diet (Diet-Med) is associated with higher dietary vitamin D intake, there are very limited data on the influence of Diet-Med on serum 25-Hydroxy Vitamin D (25OHD) levels. Our aim was to evaluate the relationship between adherence to Diet-Med and vitamin D status in obese patients.Material and Methods: Retros...

Introduction: The number of transgender men and women who seek gender-affirming therapy is rapidly increasing worldwide. It is still a population at high risk for several morbidities. The Basque Country Gender Identity Clinic was created in 2009 to centralize their medical care in the region.Aim: To determine the proportion of transgender individuals in the Basque Country, the prevalence of several morbidities in this transgender population, their evolut...

Background: A normal islet includes both mature and immature β-cells, with the former possessing higher insulin content and the latter displaying better proliferative capacity. However, it remains unknown whether immature β-cells also contribute to the regulation of insulin release, especially by commanding the activity of their mature counterparts.Materials and methods: Pdx1, Mafa, and Ngn3 were overexpressed in &#94...